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Neil Godfrey recently posted an "INFORMAL Comparison of some institutional repository solutions" that anyone trying to make a platform decision may find useful. You will no doubt need to go much deeper before making a final decision, but at least this may serve as a good summary introduction to what each platform provides.

Also keep in mind that the landscape can be slightly more complicated than depicted here. For example, with the Digital Commons solution from bepress.com, you can easily add a full-featured peer review publication system to your institutional repository. This is something you cannot do with many other IR solutions, including the popular DSpace platform. This distinction is not covered in Godfrey's informal review. But overall it isn't a bad place to start in getting to know the various solutions.